Conolidine alkaloid for chronic pain Options
Most lately, it has been determined that conolidine and the above derivatives act over the atypical chemokine receptor 3 (ACKR3. Expressed in very similar places as classical opioid receptors, it binds to the wide array of endogenous opioids. Unlike most opioid receptors, this receptor functions for a scavenger and doesn't activate a 2nd messenger